Discussion: Conditional Growth Charts
نویسندگان
چکیده
The authors are to be congratulated for a very important contribution with many practical applications. Including covariates in the construction of growth charts will undoubtedly lead to more informative tools for practitioners in many disciplines. Growth charts are widely used in practice to monitor the evolution of particular univariate measurements over time. In some situations, a patient’s evolution may be better described by the joint behavior of these variables of interest. For example, instead of using two univariate growth charts to map the weight and height of children, the physician may prefer to simultaneously locate the child’s measurements with respect to the joint population distribution of weight and height for children of the same age cohort. It is well known that biological variables are generally correlated and that these correlations may be important to determine multivariate boundaries for the “normal” range of the response vector. When measurements are correlated, univariate growth charts may be unable to represent interesting combined features of the variables of interest. We can identify the following challenges when one tries to develop multivariate growth charts:
منابع مشابه
Discussion: Conditional Growth Charts
I will use the terms “reference centiles” or “centile charts,” as the setting that I consider here is more general than that of “growth charts.” Longitudinal reference centiles over some measure of time (typically age) are almost always implemented repeatedly on the same individual. In this kind of setting the notion of conditional or adaptive centile charts is very appealing, particularly when...
متن کاملDiscussion : Conditional Growth Charts
1. Overview. Wei and He are to be congratulated on an innovative and important article. The conditional approach to growth charts described in their article is important in a practical sense, and the use of quantile regression is both natural and well motivated. We look forward to further application of their idea to actual practice, because the concept of “falling behind” in one’s growth cycle...
متن کاملDiscussion: Conditional Growth Charts
First, I would like to congratulate the authors for an interesting application of their semiparametric quantile regression model to longitudinal human growth data. On an earlier occasion, I had an opportunity to collaborate with the authors on applying this method for the purpose of constructing semilongitudinal growth charts for height and for body mass index. As my background is in medicine r...
متن کاملConditional Quantile Analysis When Covariates Are Functions, With Application to Growth Data
Motivated by the conditional growth charts problem, we develop a method for conditional quantile analysis when predictors take values in a functional space. The proposed method aims at estimating conditional distribution functions under a generalized functional regression framework. This approach facilitates balancing of model flexibility and the curse of dimensionality for the infinite-dimensi...
متن کاملConditional reference charts to assess weight gain in British infants.
Growth monitoring in infancy is a useful tool for detecting growth disorders and failure to thrive. However, current weight charts do not monitor growth as such, they only identify infants whose weight centile is low and/or falling. A reference of conditional weight gain is described which compares an infant's current weight with that predicted from their previous weight, allowing for the fact ...
متن کامل